吧友们都有遇到类似的BUG吗？

没有

我以前在东堡学院的召唤师npc遇到过类似情况，当时他没有卖东西那个选项了，我就把其他的对话点完退出，过了一会再与他对话就好了。

我装多随从mod遇到过这种情况

没遇到，我一般都是从接到黎明开始就连续做，直到全系列任务终结

我是一直带着的暗杀时也一样

试试控制台锁定大小姐以后 输入resurrect

先存档，点击大小姐用disable删除她，再用enable找回，再试试强制随从代码！

遇见过，当时就读档了

楼主真的认真百度了么。。百度“瑟拉娜”，百科里就有解法

我记得serana是02002b74

After being asked to "wait" or being dismissed as a follower, she may not have the option to follow again.
This bug is fixed by version 2.0.2 of the Unofficial Dawnguard Patch.
To bring back the "Come with me" dialogue after dismissing Serana, enter the code sqv DLC1NPCMentalModel in the console. You are given a long list of information. Scroll down the list using the up and down arrows, and make sure that the following codes: CanFollow_var = True / IsFollowing_var = True / IsWaiting_var = True / TurnOffComeWithMe_var = False / LockedIn_var = False are in order by looking at the false/true (i.e., if LockedIn_var was set to true then you need to put it to false). To do this, enter the following command: setpqv DLC1NPCMentalModel LockedIn_var False. Once you do this you should be able to recruit Serana to be your follower again.
To get Serana following again after asking her to "Wait", go somewhere far away (like inside Fort Dawnguard) and wait three to five days.

真是个悲伤的故事……bug这东西谁说得准……忍痛读档吧……反正我没遇到过

我在黎明守卫任务途中也遇到过，打主教之前发生的，resurrect，disable，enable，setrelationshiprank 4全试了一遍，根本没用……于是我就用东方随从强制跟随，大小姐依然不走一怒之下一直召唤随从拉着大小姐走，打完大主教以后和大小姐过了一段剧情，大小姐又变成跟随状态了，这会我学乖存档，再点在这等我之后对话里终于出现了跟着我的选项……